From: Exploring the role of transtibial prosthetic use in deep tissue injury development: a scoping review
Autor and year | Objective | Aetiological factor | Qualitative results |
---|---|---|---|
Mak et al. 2001 [40] | Overview over current knowledge about biomechanics in TTAa s | Deformation, impaired lymphatic system, ischemia | - Skeletal movement and friction lead to soft tissue deformation during gait - Stress and deformation affect cellular and tissue function mechanically and via impairment of ancillary systems - Magnitude, direction, distribution, duration, loading rate are crucial - Possible accumulative effect of repetitive stress |
Mak et al. 2010 [9] | Overview over tissue response to loading | Deformation, impaired lymphatic system, ischemia, ischemia-reperfusion | - Immediate muscle damage by direct mechanical insult or over longer period by ischemia - Reperfusion exacerbates damage by oxidative stress and inflammation - Damage may accumulate if insufficient recovery time |
Bader et al. 2019 [26] | Analysis of bioengineering tools for device related soft tissue damage | Deformation, lymphatic drainage, ischemia, ischemia reperfusion injury | - Direct deformation, impaired lymphatic drainage, disrupted microvasculature and ischemia reperfusion as aetiological factors - High inter-patient variability |