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Fig. 7 | BMC Biomedical Engineering

Fig. 7

From: Spiropyran as a potential molecular diagnostic tool for double-stranded RNA detection

Fig. 7

Elevation of dsRNA expression detected using MC. a Increased dsRNA expression upon decitabine treatment is confirmed for a number of ERV transcripts using qRT-PCR. The increase was statistically significant for Day 3 and Day 5 samples compared to the preceding days. b Changes in the absorbance spectra when RNAs extracted from decitabine treated cells were added to MC. TDW was used as the solvent. c Quantified percentage change showing increased dsRNA expression. Day 5 sample is statistically different from day 0 (p = 0.0037), day 1 (p = 0.0069), and day 3 (p = 0.0097). For both (a) and (c), average of three biological replicates is shown and error bars indicate s.e.m. d The absorbance spectra of MC when incubated with HCT116 RNAs treated with RNase A

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