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Table 1 ‘Scar-in-a-jar’ HCS assay metrics and compound potency for standard inhibitors

From: A high content, phenotypic ‘scar-in-a-jar’ assay for rapid quantification of collagen fibrillogenesis using disease-derived pulmonary fibroblasts

 

pIC50

Assay metrics

MEAN

STDEV

%CV

Assay window

n

Z prime

PGE2

7.65

0.98

12.7

4.64

8

0.50

SB-525334

6.79

0.33

4.8

4.63

28

0.49

CZ415

6.38

0.31

4.8

4.67

25

0.51

  1. Average pIC50, standard deviation (STDEV), and % coefficient of variance (%CV) values of the assay controls: SB-525334, PGE2 and CZ415 and assay parameters to measure assay performance and robustness
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BMC Biomedical Engineering

ISSN: 2524-4426

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