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Table 3 Studies on non-prosthesis induced risk factors for DTI

From: Exploring the role of transtibial prosthetic use in deep tissue injury development: a scoping review

Author and year

Type of Study

Objective

Non-prosthesis induced risk factors

Study Population

Qualitative Results

Henrot et al. 2000 [39]

Literature review

Overview over surgical features of amputation in relation to postoperative stump pain

Tissue Morphology

NA

- Postoperative complications: Heterotopic ossification, aggressive bone edges, pistoning, ulceration

- Extrinsic pain: caused by improper fit or alignment

- Intrinsic pain: nervous or anatomical cause

Portnoy et al. 2007 [37]

In silico study

Determination of internal stress in muscle flap of TTAa; influence of bone sharpness, tissue thickness, mechanical properties

Tissue Morphology,Mechanical Properties

- Use of data from Portnoy et al. 2007 [29]

- Increase in pressure with reduced flap thickness

- Increase in pressure with increased muscle stiffness

- No clear relationship between bone radius and pressure

Portnoy et al. 2009 [30]

Experimental study

Determination of inter-subject variability in internal tissue loads in TTA with different geometrical features during static loading

Tissue Morphology

- 5 unilateral TTAs

- Traumatic cause

- 1 female, 4 male

- Mean age 48.6 yrs.

- Mean weight 67.8 kg

- High inter-subject variability

- Risk of DTI for patients with little fat padding

- More even pressure distribution with flat compared to sharp tibial ends

- Lower strains with longer residua

Portnoy et al. 2009 [36]

In silico study

Identify influence of risk factors on internal loadingonditions in TTA

Tissue Morphology,Mechanical Properties

- 1 unilateral TTA

- Traumatic cause

- Male

- Age 44 yrs.

- Weight 82 kg

- Thicker muscle flap and increased bone radius reduce DTI risk

- Osteophyte, sharp bevelment and muscle stiffening increase risk

- Surgical scars change overall stress distribution

Kosasih et al. 1998 [28]

Experimental study

Identify sensory changes in well healed TTAs

Sensory impairment

- 9 unilateral TTAs

- Traumatic cause

- All male

- Mean age 55.4 yrs.

- Weight not specified

- No deep pressure sensory impairment in well healed TTA stumps

Mak et al. 2001 [40]

Literature review

Overview over current knowledge on biomechanics in TTAs

Sensory impairment

NA

- Neuropathy leading to usually preventable soft tissue damage

Bader et al. 2019 [26]

Literature review

Analysis of bioengineering tools for device related soft tissue damage

Sensory impairment

NA

- Risk factors: neuromuscular impairments, diabetes

  1. a Transtibial amputee