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Biomaterials, nanomedicine and tissue engineering

Scope: This section combines inter- and multidisciplinary principles across the biological, physical and chemical sciences. It focuses on the development of tools, functional substitutes and clinical strategies that repair, regenerate, preserve, or develop tissue or organ function. The section considers articles on the development of functional biomaterials, cell-assembled systems, biofabrication methods, nanomedical devices/implants, diagnostic systems, regenerative medicine therapies, drug-discovery/delivery methods, responsive systems, as well as 2D/3D tissue growth. Articles on scalability/robustness aspects and the industrial application of tissue engineering are strongly encouraged. Manuscripts focusing on stem cell biology, describing an application on a relevant clinical setting are welcome.

  1. Organoids are a reliable model used in the study of human brain development and under pathological conditions. However, current methods for brain organoid culture generate tissues that range from 0.5 to 2 mm o...

    Authors: Mariana Oksdath Mansilla, Camilo Salazar-Hernandez, Sally L. Perrin, Kaitlin G. Scheer, Gökhan Cildir, John Toubia, Kristyna Sedivakova, Melinda N. Tea, Sakthi Lenin, Elise Ponthier, Erica C. F. Yeo, Vinay Tergaonkar, Santosh Poonnoose, Rebecca J. Ormsby, Stuart M. Pitson, Michael P. Brown…

    Citation: BMC Biomedical Engineering 2021 3:6

    Content type: Methodology article

    Published on:

  2. Electric fields are involved in numerous physiological processes, including directional embryonic development and wound healing following injury. To study these processes in vitro and/or to harness electric fi...

    Authors: Christina N. M. Ryan, Meletios N. Doulgkeroglou and Dimitrios I. Zeugolis

    Citation: BMC Biomedical Engineering 2021 3:1

    Content type: Review

    Published on:

  3. A major challenge for any glaucoma implant is their ability to provide long-term intraocular pressure lowering efficacy. The formation of a low-permeability fibrous capsule around the device often leads to obs...

    Authors: Ian Grierson, Don Minckler, Marian K. Rippy, Andrew J. Marshall, Nathalie Collignon, Jessica Bianco, Benoit Detry and Murray A. Johnstone

    Citation: BMC Biomedical Engineering 2020 2:10

    Content type: Research article

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  4. Tendons link muscle to bone and transfer forces necessary for normal movement. Tendon injuries can be debilitating and their intrinsic healing potential is limited. These challenges have motivated the developm...

    Authors: Sophia K. Theodossiou and Nathan R. Schiele

    Citation: BMC Biomedical Engineering 2019 1:32

    Content type: Review

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  5. Adipose tissue is a vital tissue in mammals that functions to insulate our bodies, regulate our internal thermostat, protect our organs, store energy (and burn energy, in the case of beige and brown fat), and ...

    Authors: Connor S. Murphy, Lucy Liaw and Michaela R. Reagan

    Citation: BMC Biomedical Engineering 2019 1:27

    Content type: Review

    Published on:

  6. Excessive extracellular matrix (ECM) deposition is a hallmark feature in fibrosis and tissue remodelling diseases. Typically, mesenchymal cells will produce collagens under standard 2D cell culture conditions,...

    Authors: Robert B. Good, Jessica D. Eley, Elaine Gower, Genevieve Butt, Andrew D. Blanchard, Andrew J. Fisher and Carmel B. Nanthakumar

    Citation: BMC Biomedical Engineering 2019 1:14

    Content type: Research article

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  7. Mesenchymal stromal cells (MSCs) are widely used in clinical trials for bone repair and regeneration. Despite previous evidence showing a prominent osteogenic potential of 2D cultured CD271 enriched MSCs, the ...

    Authors: Sylvia Müller, Lyndsey Nicholson, Naif Al Harbi, Elena Mancuso, Elena Jones, Anne Dickinson, Xiao Nong Wang and Kenneth Dalgarno

    Citation: BMC Biomedical Engineering 2019 1:16

    Content type: Research

    Published on:

    The Correction to this article has been published in BMC Biomedical Engineering 2019 1:34

  8. Advancement in polymer technologies, facilitated predominantly through chemical engineering approaches or through the identification and utilization of novel renewable resources, has been a steady focus of bio...

    Authors: Katarzyna Krukiewicz, Jorge Fernandez, Małgorzata Skorupa, Daria Więcławska, Anup Poudel, Jose-Ramon Sarasua, Leo R. Quinlan and Manus J. P. Biggs

    Citation: BMC Biomedical Engineering 2019 1:9

    Content type: Research article

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  9. Adhesions represent a major burden in clinical practice, particularly following abdominal, intrauterine, pericardial and tendon surgical procedures. Adhesions are initiated by a disruption in the epithelial or...

    Authors: Héctor Capella-Monsonís, Stephen Kearns, Jack Kelly and Dimitrios I. Zeugolis

    Citation: BMC Biomedical Engineering 2019 1:5

    Content type: Review

    Published on: