|
Target RR (breaths/min)
|
Measured RR (breaths/min)
|
VT (mL/kg)
|
ΔPIP (cm H2O)
|
ΔPEEP (cm H2O)
|
SpO2 (%)
|
|---|
|
30
|
29.8 ± 2.0
|
5.8 ± 0.4
|
1.0 ± 0.4
|
−0.4 ± 0.4
|
98
|
|
40
|
39.8 ± 0.2
|
5.7 ± 0.5
|
0.1 ± 0.1
|
−0.7 ± 0.6
|
99
|
|
60
|
59.4 ± 3.5
|
5.5 ± 0.4
|
1.7 ± 0.3
|
0.0 ± 0.3
|
98
|
|
120
|
119.6 ± 2.4
|
2.9 ± 0.3
|
0.6 ± 0.5
|
0.9 ± 0.1
|
99
|
- Respiratory mechanics measured on one rabbit while ventilating at varying target RRs (30, 40, 60, and 120 breaths/min) and maintaining constant pressure settings (PIPtarget = 11 cm H2O; PEEPtarget = 3 cm H2O) for 5 min each. Measured RR, VT, ΔPIP, and ΔPEEP are presented as mean ± standard deviation from the full duration of the 5-min ventilation; SpO2 presented as mean SpO2 during the last minute of the 5-min ventilation. ΔPIP calculated as ΔPIP = PIP – PIPtarget, and ΔPEEP calculated as ΔPEEP = PEEP – PEEPtarget
- PEEP Positive end expiratory pressure, PIP Peak inspiratory pressure, RR Respiratory rate, SpO2 Blood oxygen saturation, VT Tidal volume
