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Table 2 FALCON respiratory mechanics and SpO2 at different respiratory rates

From: Efficacy and safety testing of a COVID-19 era emergency ventilator in a healthy rabbit lung model

Target RR (breaths/min)

Measured RR (breaths/min)

VT (mL/kg)

ΔPIP (cm H2O)

ΔPEEP (cm H2O)

SpO2 (%)

30

29.8 ± 2.0

5.8 ± 0.4

1.0 ± 0.4

−0.4 ± 0.4

98

40

39.8 ± 0.2

5.7 ± 0.5

0.1 ± 0.1

−0.7 ± 0.6

99

60

59.4 ± 3.5

5.5 ± 0.4

1.7 ± 0.3

0.0 ± 0.3

98

120

119.6 ± 2.4

2.9 ± 0.3

0.6 ± 0.5

0.9 ± 0.1

99

  1. Respiratory mechanics measured on one rabbit while ventilating at varying target RRs (30, 40, 60, and 120 breaths/min) and maintaining constant pressure settings (PIPtarget = 11 cm H2O; PEEPtarget = 3 cm H2O) for 5 min each. Measured RR, VT, ΔPIP, and ΔPEEP are presented as mean ± standard deviation from the full duration of the 5-min ventilation; SpO2 presented as mean SpO2 during the last minute of the 5-min ventilation. ΔPIP calculated as ΔPIP = PIP – PIPtarget, and ΔPEEP calculated as ΔPEEP = PEEP – PEEPtarget
  2. PEEP Positive end expiratory pressure, PIP Peak inspiratory pressure, RR Respiratory rate, SpO2 Blood oxygen saturation, VT Tidal volume
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BMC Biomedical Engineering

ISSN: 2524-4426

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