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Table 2 FALCON respiratory mechanics and SpO2 at different respiratory rates

From: Efficacy and safety testing of a COVID-19 era emergency ventilator in a healthy rabbit lung model

Target RR (breaths/min) Measured RR (breaths/min) VT (mL/kg) ΔPIP (cm H2O) ΔPEEP (cm H2O) SpO2 (%)
30 29.8 ± 2.0 5.8 ± 0.4 1.0 ± 0.4 −0.4 ± 0.4 98
40 39.8 ± 0.2 5.7 ± 0.5 0.1 ± 0.1 −0.7 ± 0.6 99
60 59.4 ± 3.5 5.5 ± 0.4 1.7 ± 0.3 0.0 ± 0.3 98
120 119.6 ± 2.4 2.9 ± 0.3 0.6 ± 0.5 0.9 ± 0.1 99
  1. Respiratory mechanics measured on one rabbit while ventilating at varying target RRs (30, 40, 60, and 120 breaths/min) and maintaining constant pressure settings (PIPtarget = 11 cm H2O; PEEPtarget = 3 cm H2O) for 5 min each. Measured RR, VT, ΔPIP, and ΔPEEP are presented as mean ± standard deviation from the full duration of the 5-min ventilation; SpO2 presented as mean SpO2 during the last minute of the 5-min ventilation. ΔPIP calculated as ΔPIP = PIP – PIPtarget, and ΔPEEP calculated as ΔPEEP = PEEP – PEEPtarget
  2. PEEP Positive end expiratory pressure, PIP Peak inspiratory pressure, RR Respiratory rate, SpO2 Blood oxygen saturation, VT Tidal volume