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  1. Triple tracer meal experiments used to investigate organ glucose-insulin dynamics, such as endogenous glucose production (EGP) of the liver are labor intensive and expensive. A procedure was developed to obtai...

    Authors: Mariël F. van Stee, Shaji Krishnan, Albert K. Groen and Albert A. de Graaf

    Citation: BMC Biomedical Engineering 2019 1:29

    Content type: Research Article

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  2. Adipose tissue is a vital tissue in mammals that functions to insulate our bodies, regulate our internal thermostat, protect our organs, store energy (and burn energy, in the case of beige and brown fat), and ...

    Authors: Connor S. Murphy, Lucy Liaw and Michaela R. Reagan

    Citation: BMC Biomedical Engineering 2019 1:27

    Content type: Review

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  3. Since nuclei segmentation in histopathology images can provide key information for identifying the presence or stage of a disease, the images need to be assessed carefully. However, color variation in histopat...

    Authors: Hwejin Jung, Bilal Lodhi and Jaewoo Kang

    Citation: BMC Biomedical Engineering 2019 1:24

    Content type: Research article

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  4. Leg-press devices are one of the most widely used training tools for musculoskeletal strengthening of the lower-limbs, and have demonstrated important cardiopulmonary benefits for healthy and patient populatio...

    Authors: Farouk Chrif, Tobias Nef and Kenneth J Hunt

    Citation: BMC Biomedical Engineering 2019 1:26

    Content type: Research Article

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  5. Optical mapping of transmembrane voltage and intracellular calcium is a powerful tool for investigating cardiac physiology and pathophysiology. However, simultaneous dual mapping of two fluorescent probes rema...

    Authors: Rafael Jaimes III, Damon McCullough, Bryan Siegel, Luther Swift, James Hiebert, Daniel McInerney and Nikki Gillum Posnack

    Citation: BMC Biomedical Engineering 2019 1:25

    Content type: Research article

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  6. Accurate spasticity assessment provides an objective evaluation index for the rehabilitation treatment of patients with spasticity, and the key is detecting stretch reflex onset. The surface electromyogram of ...

    Authors: Mingjia Du, Baohua Hu, Feiyun Xiao, Ming Wu, Zongjun Zhu and Yong Wang

    Citation: BMC Biomedical Engineering 2019 1:23

    Content type: Research article

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  7. Many people suffer from movement disability due to amputation or neurological diseases. Fortunately, with modern neurotechnology now it is possible to intercept motor control signals at various points along th...

    Authors: Wing-kin Tam, Tong Wu, Qi Zhao, Edward Keefer and Zhi Yang

    Citation: BMC Biomedical Engineering 2019 1:22

    Content type: Review

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  8. In virtual reality (VR) applications such as games, virtual training, and interactive neurorehabilitation, one can employ either the first-person user perspective or the third-person perspective to perceive th...

    Authors: Juan Trelles Trabucco, Andrea Rottigni, Marco Cavallo, Daniel Bailey, James Patton and G. Elisabeta Marai

    Citation: BMC Biomedical Engineering 2019 1:21

    Content type: Research article

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  9. Stroke rehabilitation often uses the motor relearning concept that require patients to perform active practice of skill-specific training and to receive feedback. Treadmill training augmented with real-time vi...

    Authors: Chanwit Phongamwong, Philip Rowe, Karen Chase, Andrew Kerr and Lindsay Millar

    Citation: BMC Biomedical Engineering 2019 1:20

    Content type: Research article

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  10. A growing need exists for neuroscience platforms that can perform simultaneous chronic recording and stimulation of neural tissue in animal models in a telemetry-controlled fashion with signal processing for a...

    Authors: John T. Ramshur, Bashir I. Morshed, Amy L. de Jongh Curry and Robert S. Waters

    Citation: BMC Biomedical Engineering 2019 1:19

    Content type: Methodology article

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  11. Organoids derived from induced pluripotent stem (iPS) or embryonic stem (ES) cells have been evaluated as in vitro models of development and disease. However, maintaining these cells under long-term static cul...

    Authors: Sachiko Sekiya, Tetsutaro Kikuchi and Tatsuya Shimizu

    Citation: BMC Biomedical Engineering 2019 1:15

    Content type: Methodology article

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  12. Therapy resistant ulcers are wounds that remain open for a long time period and often arise from chronic venous disease, prolonged pressure or diabetes. For healing of chronic wounds, revitalization of the ine...

    Authors: Hanneke N. Monsuur, Ester M. Weijers, Susan Gibbs and Lenie J. van den Broek

    Citation: BMC Biomedical Engineering 2019 1:18

    Content type: Research article

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  13. Excessive extracellular matrix (ECM) deposition is a hallmark feature in fibrosis and tissue remodelling diseases. Typically, mesenchymal cells will produce collagens under standard 2D cell culture conditions,...

    Authors: Robert B. Good, Jessica D. Eley, Elaine Gower, Genevieve Butt, Andrew D. Blanchard, Andrew J. Fisher and Carmel B. Nanthakumar

    Citation: BMC Biomedical Engineering 2019 1:14

    Content type: Research article

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  14. Mesenchymal stromal cells (MSCs) are widely used in clinical trials for bone repair and regeneration. Despite previous evidence showing a prominent osteogenic potential of 2D cultured CD271 enriched MSCs, the ...

    Authors: Sylvia Müller, Lyndsey Nicholson, Naif Al Harbi, Elena Mancuso, Elena Jones, Anne Dickinson, Xiao Nong Wang and Kenneth Dalgarno

    Citation: BMC Biomedical Engineering 2019 1:16

    Content type: Research

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  15. Due to the presence of high noise level in tomographic series of energy filtered transmission electron microscopy (EFTEM) images, alignment and 3D reconstruction steps become so difficult. To improve the align...

    Authors: Soumia Sid Ahmed, Zoubeida Messali, Larbi Boubchir, Ahmed Bouridane, Sergio Marco and Cédric Messaoudi

    Citation: BMC Biomedical Engineering 2019 1:13

    Content type: Research article

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  16. In this paper, we focus on robots used for laparoscopic surgery, which is one of the most active areas for research and development of surgical robots. We introduce research and development of laparoscope-hold...

    Authors: Kenji Kawashima, Takahiro Kanno and Kotaro Tadano

    Citation: BMC Biomedical Engineering 2019 1:12

    Content type: Review

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  17. Currently there are no standard models with which to evaluate the biomechanical performance of calcified tissue adhesives, in vivo. We present, herein, a pre-clinical murine distal femoral bone model for evaluati...

    Authors: Philip Procter, Michael Pujari-Palmer, Gry Hulsart-Billström, David Wenner, Gerard Insley, Sune Larsson and Håkan Engqvist

    Citation: BMC Biomedical Engineering 2019 1:11

    Content type: Methodology article

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  18. Advancement in polymer technologies, facilitated predominantly through chemical engineering approaches or through the identification and utilization of novel renewable resources, has been a steady focus of bio...

    Authors: Katarzyna Krukiewicz, Jorge Fernandez, Małgorzata Skorupa, Daria Więcławska, Anup Poudel, Jose-Ramon Sarasua, Leo R. Quinlan and Manus J. P. Biggs

    Citation: BMC Biomedical Engineering 2019 1:9

    Content type: Research article

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  19. In Photoacoustic imaging (PAI), the most prevalent beamforming algorithm is delay-and-sum (DAS) due to its simple implementation. However, it results in a low quality image affected by the high level of sidelo...

    Authors: Moein Mozaffarzadeh, Bahador Makkiabadi, Maryam Basij and Mohammad Mehrmohammadi

    Citation: BMC Biomedical Engineering 2019 1:10

    Content type: Research article

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  20. Frailty assessment is a critical approach in assessing the health status of older people. The clinical tools deployed by geriatricians to assess frailty can be grouped into two categories; using a questionnair...

    Authors: Yasmeen Naz Panhwar, Fazel Naghdy, Golshah Naghdy, David Stirling and Janette Potter

    Citation: BMC Biomedical Engineering 2019 1:7

    Content type: Research article

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  21. Adhesions represent a major burden in clinical practice, particularly following abdominal, intrauterine, pericardial and tendon surgical procedures. Adhesions are initiated by a disruption in the epithelial or...

    Authors: Héctor Capella-Monsonís, Stephen Kearns, Jack Kelly and Dimitrios I. Zeugolis

    Citation: BMC Biomedical Engineering 2019 1:5

    Content type: Review

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  22. Corneal endothelium (CE) images provide valuable clinical information regarding the health state of the cornea. Computation of the clinical morphometric parameters requires the segmentation of endothelial cell...

    Authors: Juan P. Vigueras-Guillén, Busra Sari, Stanley F. Goes, Hans G. Lemij, Jeroen van Rooij, Koenraad A. Vermeer and Lucas J. van Vliet

    Citation: BMC Biomedical Engineering 2019 1:4

    Content type: Methodology article

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  23. In neurology and rehabilitation the primary interest for using wearables is to supplement traditional patient assessment and monitoring in hospital settings with continuous data collection at home and in commu...

    Authors: Margit Alt Murphy, Filip Bergquist, Bengt Hagström, Niina Hernández, Dongni Johansson, Fredrik Ohlsson, Leif Sandsjö, Jan Wipenmyr and Kristina Malmgren

    Citation: BMC Biomedical Engineering 2019 1:3

    Content type: Research article

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  24. This editorial accompanies the launch of BMC Biomedical Engineering, a new open access, peer-reviewed journal within the BMC series, which seeks to publish articles on all aspects of biomedical engineering. As on...

    Authors: Alexandros Houssein, Alan Kawarai Lefor, Antonio Veloso, Zhi Yang, Jong Chul Ye, Dimitrios I. Zeugolis and Sang Yup Lee

    Citation: BMC Biomedical Engineering 2019 1:1

    Content type: Editorial

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